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Maybelle "May" Parker is a recurring character in the Marvel Cinematic Universe. She appeared as a major character in the Spider-Man trilogy, and a minor character in both Captain America: Civil War and Avengers: Endgame.

May married Ben Parker, and together they moved to Queens to look after their orphaned nephew Peter Parker. Ben eventually died and May was left to raise Peter on her own. Peter would eventually become an intern at Stark Industries, under the mentorship of Tony Stark. Unknown to her, Peter had actually become the crime-fighting vigilante Spider-Man upon being bitten by a radioactive spider. May would continue to care for Peter, but after his homecoming dance she discovered his secret identity as Spider-Man.

Two years later, May was a victim of Thanos' Infinity Snap. She was resurrected by the Hulk when he reversed the Snap, and found that five years had passed since her death. Stark would eventually sacrifice himself in the final battle against Thanos, and May attended his funeral at his house alongside Peter.

By 2024, May was a member of the Salvation Army and helped other victims of the Infinity Snap find new homes. When Peter went on a field trip around Europe, May packed his Spider-Man suit for him against his will. While he was gone, May started an affair with Stark's secretary Happy Hogan. When Peter returned, his identity as Spider-Man was exposed and May, Peter and Peter's close friends who knew his identity came under pressure.

Peter asked Doctor Strange to make it so his identity wasn't exposed, but the spell caused many villains from alternate realities to come through. May allowed Peter and the villains to use Hogan's apartment as he tried to cure them, but Green Goblin's personality grew loose and he severely injured Peter. When May tried to save him, Goblin fatally impaled May with his glider. As May lay dying in Peter's arm, she told him that "with his great power, came a great responsibility". Peter would keep her words of wisdom to heart, believing in responsibility and giving people second chances.

She was portrayed by Marisa Tomei.

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